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CAS: 60-79-7
分子式: C19H23N3O2
分子量: 325.39
中文名称: 
麦角新碱
麦角袂春
爱谷米特邻碱
爱各米特令碱
英文名称: 
n-(1-(hydroxymethyl)ethyl)-d-lysergomide
ergostetrine
ergotocine
ermetrine
l-lysergic-l(beta-hydroxyisopropylamide)
n-((S)-2-hydroxy-1-methylethyl)-lysergamid
lysergic acid propanolamide
margonovine
n-(1-(hydroxymethyl)ethyl)-d-lysergamide
ergonovine
n-(1-hydroxymethyl)ethyl)-d-lysergomide
n-(alpha-(hydroxymethyl)ethyl)-d-lysergamide
n-(alpha-(hydroxymethyl)ethyl)-d-lysergomide
neofemergen
secacornin
secometrin
9,10-Didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergdine-8-carboxamide
N-[-(Hydroxyme-thyl)ethyl]-D-lysergamide
ergobasine
9,10-didehydro-n-(alpha-(hydroxymethyl)ethyl)-6-methylergoline-8-beta-ca rbox
9,10-dihydro-n-(alpha-(hydroxymethyl)ethyl)-6-methylergoline-8-beta-carboxamide
basergin
d-lysergic acid 1-hydroxymethylethylamide
d-lysergic acid l-2-propanolamide
d-lysergic acid-l,2-propanolamide
d-lysergic acid-l-propanolamide
ergoatetrine
9,10-didehydro-n-(2-hydroxy-1-methylethyl)-6-methylergo line-8beta(S)-carboxami
ergoklinine
9,10-didehydro-n-(2-hydroxy-1-methylethyl)-6-methyl-ergoline-8-carboxamid
(8-beta(S))-
9,10-didehydro-n-(2-hydroxy-1-methylethyl)-6-methyl-ergoline-8-carboxamid (
ergoline-8beta-carboxamide, 9,10-didehydro-n-((S)-2-hydroxy-1-methylethyl)-6-me
ergometrin
ergometrine
性质描述: 白色细结晶。熔点162-163℃。易溶于低级醇类、乙酸乙酯和丙酮,微溶于氯仿。在水中的溶解度比麦角中其他生物碱为高。
生产方法: 用发酵法生产。
用途: 该品为子宫兴奋药。一般制成麦角新碱顺丁烯二酸盐(马来酸麦角新碱)。麦角制剂主要用于预防和治疗产后子宫出血及治疗子宫复原不佳等。但由于麦角制剂使子宫底及子宫颈平滑肌同时呈现收缩,不利于胎儿娩出,所以不作催产和引产用。马来酸麦角新碱对鼠静脉注射LD50为8.26mg/kg。
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