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MRE 3008F20
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MRE 3008F20图片
CAS NO:252979-43-4
包装:10mg
市场价:2930元

产品介绍
MRE 3008F20 是一种高效、高选择性的放射性腺苷 A3 受体 (AA3R) 拮抗剂 (Ki\u003d1.8 nM)。
Cas No.252979-43-4
化学名1-(2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Canonical SMILESO=C(NC(C=C1)=CC=C1OC)NC(N2N=C(C3=CC=CO3)N=C2C4=C5)=NC4=NN5CCC
分子式C21H20N8O3
分子量423.44
溶解度<21.17mg/ml in DMSO
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MRE3008F20 is a highly potent and selective antagonist of adenosine A3 receptor (AA3R), inhibits agonist-induced cAMP elevation in resting T lymphocytes with an IC50 of 5 nM[1].

References:
[1]. Gessi S, et al. Expression of A3 adenosine receptors in human lymphocytes: up-regulation in T cell activation. Mol Pharmacol. 2004 Mar;65(3):711-9.