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Imipramine-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Imipramine-d6图片
CAS NO:65100-45-0
包装与价格:
包装价格(元)
2.5mg电议
25mg电议

产品介绍
Imipramine-d6 是 Imipramine hydrochloride 的氘代物。Imipramine 是一种具有口服活性的叔胺类三环抗抑郁药。Imipramine 是一种具有抗肿瘤活性的Fascin1抑制剂。Imipramine 也抑制 5-羟色胺转运体 (serotonin transporter),其IC50值为 32 nM。Imipramine 刺激 U-87MG 胶质瘤细胞自噬(autophagy),诱导 HL-60 细胞凋亡(apoptosis)。Imipramine 具有神经保护和免疫调节作用。
生物活性

Imipramine-d6 is the deuterium labeled Imipramine hydrochloride. Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is aFascin1inhibitor with antitumor activities. Imipramine also inhibitsserotonin transporterwith anIC50value of 32 nM. Imipramine stimulates U-87MG glioma cellsautophagyand induces HL-60 cellapoptosis. Imipramine shows neuroprotective and immunomodulatory effects[1][2][3][4][5][6].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

286.44

Formula

C19H18D6N2

CAS 号

65100-45-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.