Sumatriptan (GR 43175 free base) 是一种具有口服活性的 5-HT1 受体激动剂,对 5-HT1D、5-HT1B 和 5-HT1A 受体的 Kis 分别为 17 nM、27 nM 和 100 nM。
Cas No. | 103628-46-2 |
别名 | 舒马曲坦,GR 43175 free base |
化学名 | 1-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-N-methylmethanesulfonamide |
Canonical SMILES | CNS(CC1=CC(C(CCN(C)C)=CN2)=C2C=C1)(=O)=O |
分子式 | C14H21N3O2S |
分子量 | 295.40 |
溶解度 | ≥ 14.77mg/mL in DMSO |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Sumatriptan succinate is a selective 5-HT1 receptor agonist with specificity towards 5-HT1D, 5-HT1B and 5-HT1A. In addition, the physicochemical properties of Sumatriptan succinate can be characterized using FT-IR, HPLC, SEM and XRD. |