Phyllomedusin

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Phyllomedusin

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

26145-48-2

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

Phyllomedusin，一种速激肽十肽，是一种NK1 受体激动剂。Phyllomedusin 具有血管舒张活性并引起幽门收缩。

生物活性

Phyllomedusin, an tachykinin decapeptide, is aNK1receptoragonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus^[1]^[2]^[3].

IC₅₀& Target^[1]

NK1

体外研究
(In Vitro)

Phyllomedusin increases neuronal excitation with psychoactive and behavioral responses^[4].
Phyllomedusin can cause smooth muscle contraction and vasodilatation^[4].

体内研究
(In Vivo)

Phyllomedusin (30-300 μg/kg, i.p.) delays gastric emptying in conscious rats^[2].
Phyllomedusin (0.1 and 5 μg/kg, i.v.) has stimulant activity on the stomach of the anaesthetized rat^[3].

Animal Model:	Conscious rats^[2].
Dosage:	30, 100, 300 μg/kg
Administration:	Intraperitoneal injection (i.p.)
Result:	Caused 75% delay in gastric emptying in conscious rats.

分子量

1171.37

Formula

C₅₂H₈₂N₁₆O₁₃S

CAS 号

26145-48-2

Sequence Shortening

{Pyr}-NPNRFIGLM-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.