您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Sulfadoxine
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Sulfadoxine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sulfadoxine图片
CAS NO:2447-57-6
包装:50mg
市场价:525元

产品介绍
磺胺多辛(Sulphadoxine)是一种长效磺胺类药物,通常与其他药物联合使用,用于呼吸道、泌尿道和疟疾感染。
Cas No.2447-57-6
别名磺胺多辛; Sulphadoxine
化学名4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
Canonical SMILESCOC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N
分子式C12H14N4O4S
分子量310.33378
溶解度DMF: 50 mg/ml,DMSO: 50 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 0.3 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract and malarial infections.Target: AntiparasiticSulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide. Sulfadoxine is often used in combination with pyrimethamine to treat or prevent malaria. Both drugs are antifolates; they inhibit the production of enzymes involved in the synthesis of folic acid within the parasites. Either drug by itself is only moderately effective in treating malaria, because the parasite Plasmodium falciparum may be able to use exogenous folic acid, i.e. folic acid which is present in the parasite's environment, while in combination, the two substances have a synergistic effect which outbalances that ability [1, 2].

References:
[1]. http://www.malaria-ipca.com/sulphadoxine_pyrimethamine.html
[2]. http://en.wikipedia.org/wiki/Sulfadoxine/pyrimethamine