Spiperone hydrochloride (Spiroperidol hydrochloride) 是一种选择性多巴胺 D2 受体(D2、D3、D4、D1 和 D5 受体的 Ki 值分别为 0.06 nM、0.6 nM、0.08 nM、~350 nM、~3500 nM)和 5-HT2A /5-HT1A 受体 (Kis of 1 nM/49 nM) 拮抗剂。
Cas No. | 2022-29-9 |
别名 | 螺哌隆盐酸盐,Spiroperidol hydrochloride |
化学名 | 8-(4-(4-fluorophenyl)-4-oxobutyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one hydrochloride |
Canonical SMILES | FC1=CC=C(C=C1)C(CCCN2CC[C@@]3(CC2)N(C4=CC=CC=C4)CNC3=O)=O.Cl |
分子式 | C23H26FN3O2.HCl |
分子量 | 431.94 |
溶解度 | ≥ 13.75mg/mL in DMSO |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |