| CAS NO: | 149-64-4 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 20mg | 电议 |
| Cas No. | 149-64-4 |
| 别名 | 丁溴东莨菪碱,Hyoscine butylbromide; (-)-Scopolamine butylbromide; Butylscopolamine bromide |
| Canonical SMILES | O=C([C@H](C1=CC=CC=C1)CO)O[C@H]2C[C@@H]3[N@@+](CCCC)(C)[C@H](C2)[C@H]4O[C@@H]34.[Br-] |
| 分子式 | C21H30NO4Br |
| 分子量 | 440.37 |
| 溶解度 | ≥ 12.5mg/mL in DMSO |
| 储存条件 | Store at 4°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Scopolamine butylbromide is a competitive antagonist of muscarinic acetylcholine receptor (mAChR) with an IC50 of 55.3 ± 4.3 nM.Target: mAChRScopolamine (USAN), also known as levo-duboisine and hyoscine, sold as Scopoderm, is a tropane alkaloid drug with muscarinic antagonist effects. It is among the secondary metabolites of plants from Solanaceae (nightshade) family of plants, such as henbane, jimson weed (Datura), angel's trumpets (Brugmansia), and corkwood (Duboisia). Scopolamine exerts its effects by acting as a competitive antagonist at muscarinic acetylcholine receptors, specifically M1 receptors; it is thus classified as an anticholinergic, antimuscarinic drug. Its use in medicine is relatively limited, with its chief uses being in the treatment of motion sickness and postoperative nausea and vomiting. Scopolamine is named after the plant genus Scopolia. The name "hyoscine" is from the scientific name for henbane, Hyoscyamus niger. References: |
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