Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitiveDNA polymerasesinhibitor (with respect to dATP) and a substrate ofHIVtype 1 (HIV-1)reverse transcriptase(RT)^[1].

Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and e, with values for the K_ifor PMPApp (^PMPAppK_i) relative to the K_mfor dATP (^dATPKm) of 10.2, 10.2, and 15.6, respectively^[1].

548.36

Solid

C₁₅H₃₁N₆O₁₀P₃

2122333-63-3

替诺福韦二磷酸酯三乙胺

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)