Acetyl-Calpastatin (184-210) (human) 是一种有效、选择性和可逆的钙蛋白酶抑制剂，对 μ-calpain 和组织蛋白酶 L 的 Ki 值分别为 0.2 nM 和 6 μM。
| Cas No. | 123714-50-1 |
| 别名 | 乙酰钙蛋白酶抑制蛋白(184-210)(人) |
| Canonical SMILES | CC[C@]([C@@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@]1([H])CCCN1C([C@](/N=C(O)/C)([H])CC(O)=O)=O)([H])CCSC)([H])CO)([H])CO)([H])[C@@](O)([H])C)([H])CC2=CC=C(O)C=C2)([H])/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N |
| 分子式 | C142H230N36O44S |
| 分子量 | 3177.65 |
| 溶解度 | Soluble to 5 mg/ml in Water |
| 储存条件 | Desiccate at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Selective calpain inhibitor. Strongly inhibits calpain I (Ki= 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki= 6 μM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio. |
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