KD-026 是具有口服活性的、肠细胞特异性的微粒体甘油三酯转移蛋白 (MTP)抑制剂，IC50为 8.0 nM。KD-026 在糖尿病2型中有研究的价值。

KD-026, a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.

KD-026 shows inhibitory effect against apolipoprotein B (IC50 = 9.6 nM) but no effect on apolipoprotein A1 secretion in Caco-2 cells[1].

In rats, KD-026 (30 mg/kg) reduced postprandial lipids by 50% (ED50 = 7 mg/kg)[1].

913541-47-6

C31H25F3N2O4

546.54

SLx 4090;KD026;SLx-4090;SLx4090

DMSO:55 mg/ml (100.63 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years