Erianin 能抑制吲哚胺-2,3-双加氧酶诱导的肿瘤血管生成,可用作退烧药和止疼剂。
产品描述
Erianin is a nature product extracted from Dendrobium chrysotoxum, has notable antitumour activity , can cause extensive tumour necrosis, growth delay. Erianin has antiangiogenic action by inhibiting endothelial metabolism in a JNK/SAPK-dependent manner and inducing endothelial cytoskeletal disorganisation. Erianin shows potent inhibitory activity on the proliferation of HL-60 cells, the inhibition might be relative to the apoptosis induced by Erianin and the altered expression of bcl-2 and bax genes in HL-60 cells.
Cas No.
95041-90-0
分子式
C18H22O5
分子量
318.369
储存和溶解度
DMSO:57 mg/mL(179 mM)
Chloroform, Dichloromethane, Ethyl Acetate:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years