Desoxyrhaponticin 是来自西藏营养食品唐古特大黄中的一种二苯乙烯苷。它是脂肪酸合成酶抑制剂，抑制细胞内FAS活性，下调人乳腺癌MCF-7细胞中FAS的表达。它是控制糖尿病餐后高血糖的潜在药物。

1. Desoxyrhaponticin is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney. 2. Desoxyrhaponticin and rhaponticin could be considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.

30197-14-9

C21H24O8

404.415

脱氧土大黄苷;去氧土大黄苷;Deoxyrhaponticin;Deoxyrhapontin

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years