GSK-3β inhibitor 2 (Compound 3) is a highly potent, specific and orally bioavailable GSK-3β inhibitor with an IC50 of 1.1 nM. GSK-3β inhibitor 2 can cross the blood-brain barrier. GSK-3β inhibitor 2 has the highly potential for Alzheimer's disease. References: [1]. Sivaprakasam P, et al. Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg Med Chem Lett. 2015 May 1;25(9):1856-63.

纯度：≥98%

CAS：1702428-31-6