TWS119 是一种GSK-3β特异性抑制剂,IC50值为 30 nM,它可激活 wnt/β-CATenin 信号通路,能够诱导神经元分化。
产品描述
TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation
体内活性
A cell population that expressed low levels of CD44 and high levels of CD62L on the cell surface when 30 mg/kg of TWS119 is administered. [4]
Cas No.
601514-19-6
分子式
C18H14N4O2
分子量
318.33
储存和溶解度
Ethanol:<1 mgml
DMSO:60 mg/mL (188.5 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years