Almonertinib 是EGFR激活突变抑制剂和EGFR T790M耐受突变抑制剂，对 EGFR 致敏和 T790M 耐药突变具有高选择性，用于非小细胞肺癌的研究。它对 T790M、T790M/L858R 和 T790M/Del19 表现出较强的抑制活性，对野生型的抑制作用较弱。

Hs-10296 is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.

1899921-05-1

C30H35N7O2

525.657

阿美替尼;HS-10296

Ethanol:6 mg/mL (11.41 mM)
DMSO:100 mg/mL (190.24 mM)
H2O:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years