Icotinib Hydrochloride 是一种口服的基于喹唑啉的表皮生长因子受体 (EGFR) 抑制剂，IC50值为5 nM，具有潜在的抗肿瘤活性。

Icotinib Hydrochloride is the hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of EGFR, with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, has been upregulated in a variety of cancer cell types.

1204313-51-8

C22H22ClN3O4

427.89

盐酸埃克替尼;BPI-2009H;埃克替尼盐酸盐

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years