4-MMPB 是一种选择性15-脂氧合酶抑制剂，其IC50值为 18 μM，具有前列腺癌的研究潜力。它对大豆 15-脂氧合酶和人 15-脂氧合酶-1 的 IC50 分别为 19.5 μM 和 19.1 μM。

15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer.

15-Lipoxygenase Inhibitor 1 has an IC50 of 69.6 μM for DPPH bleaching；15-Lipoxygenase Inhibitor 1 (41.48 μM; 72 hours) induces apoptosis and DNA damage in PC-3 Cells[1][2].

928853-86-5

C16H19N5S

313.42

15-Lipoxygenase Inhibitor 1

DMSO:8mg/mL (25.52mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years