(1S,2S)-Bortezomib 是 Bortezomib 的对映异构体。 Bortezomib 是一种可逆的选择性蛋白酶体抑制剂，对 20S 蛋白酶体的 Ki 为 0.6 nM。

(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a reversible and selective inhibitor of the proteasome with a Ki of 0.6 nM for 20S proteasome.

Bortezomib disrupts the cell cycle, induces apoptosis, inhibits NF-κB, and possesses anti-cancer capacity[1].

1132709-14-8

C19H25BN4O4

384.24

硼替佐米(1S,2S);Bortezomib

DMSO:40 mg/mL (104.1 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years