Daptomycin 是脂肽类抗生素,在体外快速灭活革兰氏阳性细菌。
产品描述
Daptomycin is a cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA.
体内活性
Daptomycin at a dose of 10 mg/kg given twice daily, resulted in a reduction in the number of organisms per kidney significantly compared with that in infected untreated controls within 48 h after the initiation of therapy. At 20 mg/kg given once a day, daptomycin is less effective but reduces colony counts significantly after 4 days of therapy, and its activity is comparable to that of vancomycin or vancomycin-gentamicin given twice daily[4].
Cas No.
103060-53-3
分子式
C72H101N17O26
分子量
1620.693
别名
达托霉素;LY146032
储存和溶解度
H2O:32.4 mg/mL (20 mM)
DMSO:162.1 mg/mL (100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years