Propantheline bromide 是一种抗毒蕈碱剂，用于研究多汗症，遗尿，胃肠和膀胱痉挛。

Propantheline bromide competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle.

50-34-0

C23H30BrNO3

448.401

溴丙胺太林;Pro-Banthine;Neometantyl;Neopepulsan;Propantheline bromide

DMSO:198.5 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years