Benzyldodecyldimethylammonium chloride dihydrate 是一种季铵化合物，可以用作杀虫试剂，可以靶向耐药性细菌，如耐甲氧西林金黄色葡萄球菌、耐多药铜绿假单胞菌等。它是一种抗菌试剂，其抑菌或杀菌性能取决于浓度。

Benzyldodecyldimethylammonium chloride dihydrate is a quaternary ammonium compound (QAC). Benzyldodecyldimethylammonium chloride dihydrate can be used as a biocide to target antibiotic-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), multidrug-resistant (MDR) P. aeruginosa et. al. Benzyldodecyldimethylammonium chloride dihydrate, an antimicrobial agent, bacteriostatic or bactericidal properties depending on the concentration[1][2].

Benzyldodecyldimethylammonium chloride dihydrate interacts strongly with cell surfaces in a concentration-dependent manner, and binds by ionic and hydrophobic interactions to microbial membrane surfaces, as manifested by phenomena such as membrane disruption and loss of membrane integrity with consequent leakage of essential intracellular constituents, which promote significant and irreversible changes in the cell structure[2]. Benzyldodecyldimethylammonium chloride dihydrate (0-40 mg/L; 0-24 hours) inhibits P. fluorescens with a MIC of 20 mg/L. At 5 mg/L, cells have the same growth behaviour as the control. At concentrations of 10 and 15 mg/L the growth profile is different from the control, and the cells start to grow only after 8 h of adaptation. At concentrations of ≥20 mg/L, BDMDAC inhibits cell growth[2].

Benzyldodecyldimethylammonium chloride dihydrate (1-10 μM; 2 hours) results in a dose-dependent changes in the percent population of dead rat thymocyte cells[1].

147228-80-6

C21H42ClNO2

376.02

Benzyldodecyldimethylammonium Chloride Dihydrate

DMSO:99 mg/mL (263.28 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years