C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin and in human plasma where it is positively correlated with insulin resistance in obese humans. C20 sphingomyelin is also upregulated in the liver of a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder. The plasma concentration of C20 sphingomyelin is decreased in men with prostate cancer.

121999-68-6

C43H87N2O6P

759.13

C20 Sphingomyelin (d18:1/20:0)

Chloroform:Methanol (14:1):Soluble
Methanol:Soluble
Ethanol:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years