QH536 (Compound 29) 是一种有效的HMGCR降解剂，EC50为 0.22 μM。QH536 无诱导胆固醇在细胞内积聚的副作用。QH536 具有抗炎作用，可用于心血管疾病和非酒精性脂肪性肝炎的研究。

QH536 (Compound 29) is a potent HMGCR degrader with an EC 50 of 0.22 μM. QH536 has no side-effect of inducing cholesterol accumulation in cells. QH536 shows anti-inflammatory and can be used for cardiovascular disease and nonalcoholic steatohepatitis research [1].

2754254-07-2

C33H49N3O3

535.76

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years