Toralactone 是一种分离自决明子中的天然产物,通过 Nrf2 依赖性抗氧化机制介导肝脏保护作用。
产品描述
Toralactone is a natural product isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism
体外活性
Rubrofusarin and toralactone can enhance the cytotoxic profile of P-gp substrates, such as PTX, via inhibiting P-gp efflux activity and enhancing the intracellular entrapment of P-gp substrates.?Toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity[1].
Cas No.
41743-74-2
分子式
C15H12O5
分子量
272.256
别名
toralactone
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years