DBCO-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
体外活性
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
1427004-19-0
分子式
C34H39N3O10
分子量
649.69
别名
DBCO-PEG4-NHS ester
储存和溶解度
DMSO:79 mg/mL (121.59 mM,Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years