3-(2,6-dichlorobenzyl)-1-hexadecyl-2-methyl-1H-imidazol-3-ium iodide是果糖1,6-二磷酸醛缩酶的有效抑制剂。
产品描述
3-(2,6-dichlorobenzyl)-1-hexadecyl-2-methyl-1H-imidazol-3-ium iodide is a potent inhibitor of fructose-1,6-bisphosphate aldolase.
体内活性
In mice, AMPK activity in liver can be activated by inhibiting aldolase activity. In obese mice fed with high-fat diet, 3-(2,6-dichlorobenzyl)-1-hexadecyl-2-methyl-1H-imidazol-3-ium iodide (oral administration, 1 mg/kg, once a day for two weeks) can effectively inhibit the activity of aldolase and activate the activity of AMPK in the liver of mice.
Cas No.
T60222
分子式
C27H43Cl2IN2
分子量
593.45
别名
3-(2,6-dichlorobenzyl)-1-hexadecyl-2-methyl-1H-imidazol-3-ium iodide
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years