SENP1-IN-2 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 30. SENP1-IN-2 is developed for tumor radiosensitivity enhancement.

SENP1-IN-2 may improve the sensitivity of tumor cells to irradiation[1]. SENP1-IN-2 (0.7-20 μM; 72 hours) has cytotoxic for Hella cells with an IC 50 of >20 μM[1]. Cell Cytotoxicity Assay[1]Cell Line: Hela cells Concentration: 0.7 μ M, 2.2 μM, 6.6 μM, 20 μM Incubation Time: 72 hours Result: IC 50 >20 μM

2416910-70-6

C36H60N2O5

600.885

SENP1-IN-2;SENP1-IN-2

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years