Oxantel pamOATe 是驱虫剂，有效针对Trichuris muris和钩虫。

Oxantel pamoate is used as an Antinematodal agent.

The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus[1].

68813-55-8

C36H32N2O7

604.659

酚嘧啶扑蛲灵;Oxantel embonate;Oxantel Pamoate

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years