FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET assay, respectively. FMF-04-159-2 is a covalent CDK14 inhibitor.

FMF-04-159-2 inhibits HCT116 proliferation with an IC50 of 1,144±190 nM.

2364489-81-4

C28H30Cl3N7O5S

683.01

FMF-04-159-2

DMSO:250 mg/mL (366.03 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years