Transcrocetin meglumine salt is a natural product isolated from saffron (Crocus sativus L.) and is a high-affinity antagonist of the NMDA receptor.

Transcrocetin (trans-Crocetin) shown to exert strong NMDA receptor affinity and is thought to be responsible for the CNS activity of saffron.Cellular mitochondrial dehydrogenase activity of Caco-2 cells is measured by MTT assay after a 24 h incubation period with the test compounds: Hydroalcoholic saffron extract saffron extract (SE, 0.5-1 mg/mL) and crocin-1 (250-1000 μM) reveal no negative significant changes in cellular viability. Transcrocetin at 10 μM level does not change viability while higher concentrations (40-160 μM) reduces significantly cellular viability.

T13198

C34H58N2O14

718.83

trans-Crocetin meglumine salt;Transcrocetin meglumine salt

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years