SM04554 (Dalosirvat, Wnt pathway activator 1), a novel activator of Wnt with an IC50s of 28-29 nM, is an experimental drug that shows promise for treating androgenetic alopecia (male pattern baldness). It is applied topically to the scalp – like minoxidil – but works by selectively activating and deactivating WNT signalling pathways.