OUP-16 is a potent and selective histamine H4 receptor agonist. OUP-16 is a full hH4R agonist with 40-fold selectivity over the hH3R and superior to its (2S,5S)-configured optical antipode. The H4R is expressed in various cells of the immune system, suggesting a role in inflammatory, autoimmune, and allergic disorders. References: Araki L, Harusawa S. [Synthetic studies of imidazole C-nucleosides toward biofunctional molecules]. Yakugaku Zasshi. 2010 Dec;130(12):1707-24. Review. Japanese. PubMed PMID: 21139399.

纯度：≥98%

CAS：1038917-11-1