NPD926 is an inducer of cancel cell death. NPD926 sensitized cells to inhibitors of system x(c)?, a cystine-glutamate antiporter considered to be a potential therapeutic target in cancers including cancer stem cells. Induction of excessive levels of reactive oxygen species (ROS) by small-molecule compounds has been considered a potentially effective therapeutic strategy against cancer cells, which are often subjected to chronic oxidative stress. References: Kawamura T, Kondoh Y, Muroi M, Kawatani M, Osada H. A small molecule that induces reactive oxygen species via cellular glutathione depletion. Biochem J. 2014 Oct 1;463(1):53-63. doi: 10.1042/BJ20140669. PubMed PMID: 25011393.

纯度：≥98%

CAS：384361-79-9