RS-0406 is a novel beta-sheet breaker, RS-0406 reverses amyloid beta-induced cytotoxicity and impairment of long-term potentiation in vitro. RS-0406 arrests amyloid-beta oligomer-induced behavioural deterioration in vivo. References: Kalhor HR, Jabbari MP. Inhibition Mechanisms of a Pyridazine-Based Amyloid Inhibitor: As a β-Sheet Destabilizer and a Helix Bridge Maker. J Phys Chem B. 2017 Aug 17;121(32):7633-7645. doi: 10.1021/acs.jpcb.7b05189. Epub 2017 Aug 3. PubMed PMID: 28771005.

纯度：≥98%

CAS：530112-00-6