NiraparibmetaboliteM1是niraparib的代谢物。Niraparib是一种新颖的PARP抑制剂。
CAS：1476777-06-6
分子式：C19H19N3O2
分子量：321.37
纯度：98%
存储：Store at -20°C

Background:

Niraparib metabolite M1 is a metabolite of niraparib, and the latter one acts as a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.

Niraparib metabolite M1 has the validation in plasma and urine for the support of clinical studies such as the mass balance study and the absolute bioavailability study[1].

[1]. van Andel L, et al. Liquid chromatography-tandem mass spectrometry assay for the quantification of niraparib and its metabolite M1 in human plasma and urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 19;1040:14-21.