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Dexchlorpheniramine(maleate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dexchlorpheniramine(maleate)图片
CAS NO:2438-32-6
规格:98%
分子量:390.9
包装与价格:
包装价格(元)
500mg电议
1g电议

产品介绍
Dexchlorpheniramine is a histamine H1 receptor antagonist with a pA2 value of 9.36 in guinea pig ileal tissue in vitro.
CAS:2438-32-6
分子式:C16H19ClN2.C4H4O4
分子量:390.9
纯度:98%
存储:Store at -20°C

Background:

Dexchlorpheniramine is a histamine H1 receptor antagonist with a pA2 value of 9.36 in guinea pig ileal tissue in vitro. It inhibits the proliferation of previously sensitized, allergen-challenged peripheral blood mononuclear cells by 92% at a concentration of 4.8 µM. Dexchlorpheniramine reduces noradrenaline uptake in the rat vas deferens ex vivo in response to tyramine stimulation when used at a concentration of 10 µM. In vivo, dexchlorpheniramine increases the pain threshold of mice exposed to thermal and chemical stimulation tests when administered intraperitoneally at a dose of 30 mg/kg. Formulations containing dexchlorpheniramine have been used for the treatment of allergic reactions.