生物活性
Tamoxifen Citrate是哺乳动物甾醇异构酶的选择性和有效抑制剂。
靶点信息
化学数据
| 目录号 | A10885 |
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 563.6 |
| Formula | C26H29NO.C6H8O7 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 54965-24-1 |
| Synonyms | Istubal |
| SMILES | CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
溶解度
| In vitro (25°C) | DMSO | 95 mg/mL (168.54 mM) |
| Water | Insoluble |
| Ethanol | 95 mg/mL |
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 17.74 mL | 88.72 mL | 177.43 mL |
| 0.5 mM | 3.55 mL | 17.74 mL | 35.49 mL |
| 1 mM | 1.77 mL | 8.87 mL | 17.74 mL |
| 5 mM | 0.35 mL | 1.77 mL | 3.55 mL |
*The above data is based on the productmolecular weight 563.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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