Extracted from Ligusticum chuanxiong Hort;Store the product in sealed,cool and dry condition
CAS：76494-51-4
分子式：C8H12N2.HCl.2H2O
分子量：172.66
纯度：98%
存储：Store at -20°C

Background:

Ligustrazine (hydrochloride) is a natural product.IC50 value:Target:In vitro: Ligustrazine hydrochloride displayed a protection effect on injured ECV304 cells, NOS and NO formation were significantly increased compared with the model group [1].In vivo:

参考文献:
[1]. Xu D, et al. Protective effect of ligustrazine hydrochloride on homocysteine-injured ECV304 cells. Zhongguo Zhong Yao Za Zhi. 2012 Jun;37(12):1836-9.
[2]. Wang Q, et al. Brain microdialysate, CSF and plasma pharmacokinetics of ligustrazine hydrochloride in rats after intranasal and intravenous administration. Biopharm Drug Dispos. 2013 Oct;34(7):417-22.