BW-A78U是一个PDE4抑制剂,其IC50值为3μM。
CAS:101155-02-6
分子式:C13H12FN5
分子量:257.27
纯度:98%
存储:Store at -20°C
Background:
BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM.
BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release. BW-A 78U is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release[1].
[1]. Boichot E, et al. Anti-inflammatory activities of a new series of selective phosphodiesterase 4 inhibitors derivedfrom 9-benzyladenine. J Pharmacol Exp Ther. 2000 Feb;292(2):647-53.