Chelidonine is a benzophenanthridine alkaloid that has been isolated from C.
CAS:476-32-4
分子式:C20H19NO5
分子量:353.4
纯度:98%
存储:Store at -20°C
Background:
Chelidonine is a benzophenanthridine alkaloid that has been isolated from C. majus. It induces Bcl-2- and caspase-dependent apoptosis in HepG2 human liver carcinoma cells with an LC50 value of 12 µM and in Jurkat human T cells when used at a concentration of 1 µM. Chelidonine also downregulates hTERT expression in HepG2 cells, reduces telomerase activity, and induces cell senescence.