MMP3 inhibitor 1 是一种有效的高选择性 MMP-3 抑制剂,IC50 为 1 nM。
CAS:312930-75-9
分子式:C23H31N3O6S
分子量:477.57
纯度:98%
存储:Store at -20°C
Background:
MMP3 inhibitor 1 is a potent and highly selective MMP-3 inhibitor with an IC50 of 1 nM[1].
MMP3 inhibitor 1 (Compound 27) inhibits MMP-1, MMP-2, MMP-9, and MMP-14 with IC50s of 14000, 529, 2420, and 20100 nM, respectively[1].
参考文献:
[1]. Whitlock GA, et al. A novel series of highly selective inhibitors of MMP-3. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6750-3.