Topoisomerase II inhibitor,intracellular ion chelator,cardioprotective agent
CAS：149003-01-0
分子式：C11H16N4O4.HCl
分子量：304.73
纯度：98%
存储：Store at -20°C

Background:

Dexrazoxane hydrochloride (ICRF-187 hydrochloride) is a cardioprotective agent.

参考文献:
[1]. Hasinoff BB. The use of dexrazoxane for the prevention of anthracycline extravasation injury. Expert Opin Investig Drugs. 2008 Feb;17(2):217-23.
[2]. Jones RL. Utility of dexrazoxane for the reduction of anthracycline-induced cardiotoxicity. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1311-7.
[3]. Lipshultz SE, Scully RE, Lipsitz SR et al. Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial. Lancet Oncol. 2010 Oct;11(10):950-61.