BS3 Crosslinker disodium 是一种不可降解 (non-cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
货号:ajcx34592
CAS:127634-19-9
分子式:C16H18N2Na2O14S2
分子量:572.43
溶解度:DMSO : 125 mg/mL (218.37 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.