Cyclopyrimorate是一种高效的水稻白化除草剂，靶向尿黑酸茄尼酯转移酶(HST)。HST是质体醌生物合成途径中4-羟基苯丙酮酸双加氧酶的下游酶。
货号:ajcx30454
CAS:499231-24-2
分子式:C19H20ClN3O4
分子量：389.83
溶解度:DMSO: 250 mg/mL (641.31 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Cyclopyrimorate, a highly effective bleaching herbicide for weed control in rice fields, targets homogentisate solanesyltransferase (HST). HST is a downstream enzyme of 4-hydroxyphenylpyruvate dioxygenase in the plastoquinone (PQ) biosynthesis pathway[1][2].

Cyclopyrimorate-dependent bleaching effect on Arabidopsis thaliana is reversed by decyl PQ, suggesting that this symptom is attributable to the inhibition of PQ biosynthesis[1].

[1]. Shino M, et al. In vivo and in vitro evidence for the inhibition of homogentisate solanesyltransferase by cyclopyrimorate. Pest Manag Sci. 2019 Nov 27. [2]. Shino M, et al. Action mechanism of bleaching herbicide cyclopyrimorate, a novel homogentisate solanesyltransferase inhibitor. J Pestic Sci. 2018 Nov 20;43(4):233-239.