| 规格: | 98% |
| 分子量: | 537.56 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
Background:
Dual α9β1/α4β1 integrin inhibitor; rapidly and preferentially mobilizes HSCs and progenitors. Augments HSC mobilization in combination with AMD3100 . High affinity fluorescent derivative R-BC154 also available.
Cao et al (2014) Design, synthesis and binding properties of a fluorescent α9β1/α4β1 integrin antagonist and its application as an in vi Org.Biomol.Chem. 12 965 PMID:24363056 |Pepinsky et al (2002) Comparative assessment of the ligand and metal ion binding properties of integrins α9β1 and α4β1. Biochemistry 41 7125 PMID:12033947 |Cao et al (2016) Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist. Nat.Commun. 7 11007 PMID:26975966
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