THPN 是一种有效的 Nur77 激动剂。
货号:ajcx27336
CAS:100079-26-3
分子式:C15H22O4
分子量：266.33
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Nur77 agonist. Binds Nur77 and promotes translocation of the receptor to the mitochondria resulting in autophagy in melanoma cell lines.

Wang et al (2014) Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat.Chem.Biol. 10 133 PMID:24316735 |Li et al (2015) Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation. Nat.Chem.Biol. 11 339 PMID:25822914