PKI 14-22 amide,myristoylated TFA 是一种有效的 cAMP 依赖性 PKA 抑制剂。PKI 14-22 amide,myristoylated TFA 可降低 IgG 介导的吞噬反应,也可抑制中性粒细胞粘附。
货号:ajcx32570
CAS:N/A
分子式:C55H101F3N20O14
分子量:1323.51
溶解度:H2O : 1.85 mg/mL (1.40 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
PKI 14-22 amide,myristoylated TFA is a potent cAMP-dependent PKA inhibitor. PKI 14-22 amide,myristoylated TFA reduces the IgG-mediated phagocytic response and also inhibits neutrophil adhesion[1].
参考文献:
[1]. L Ydrenius, et al. Activation of cAMP-dependent protein kinase is necessary for actin rearrangements in human neutrophils during phagocytosis. J Leukoc Biol. 2000 Apr;67(4):520-8.