A dual inhibitor of PI3Kα and mTOR
货号:ajcx23742
CAS:1246535-95-4
分子式:C16H20N8O
分子量：340.4
溶解度:Chloroform: 0.5mg/mL
纯度：98%
存储：Store at -20°C
库存：
现货Background:
VS-5584 analog is a dual inhibitor of PI3Kα and mammalian target of rapamycin (mTOR; IC50s = 17 and 150 nM, respectively).1It is a desmethyl analog of the dual PI3K/mTOR inhibitor VS-5584 .
1.Poulsen, A., Nagaraj, H., Lee, A., et al.Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602J. Chem. Inf. Model54(11)3238-3250(2014)
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