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Decitabine-15N4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Decitabine-15N4图片
包装:1mg
规格:98%
市场价:5556元
分子量:232.2

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx22218
CAS:N/A
分子式:C8H12[15N]4O4
分子量:232.2
溶解度:DMSO: slightly soluble,Methanol: slightly, heated
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Decitabine-15N4is intended for use as an internal standard for the quantification of decitabine . Decitabine is a 2'-deoxy analog of 5-azacytidine that induces dose-dependent inhibition of DNA methyltransferases and hypomethylation of DNA.1,2,3This action is useful in conditions characterized by DNA hypermethylation, as is found in myelodysplastic syndromes.4


1.Esteller, M.Epigenetics in cancerN. Engl. J. Med.3581148-1159(2008) 2.Lyko, F., and Brown, R.DNA methyltransferase inhibitors and the development of epigenetic cancer therapiesJ. Natl. Cancer Inst.97(20)1498-1506(2005) 3.Stresemann, C., Brueckner, B., Musch, T., et al.Functional diversity of DNA methyltransferase inhibitors in human cancer cell linesCancer Res.66(5)2794-2800(2006) 4.Ornstein, M.C., and Sekeres, M.A.Combination strategies in myelodysplastic syndromesInt. J. Hematol.9526-33(2012)